Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake
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منابع مشابه
Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake
Huperzine A (Hup-A) is a poorly water-soluble drug with low oral bioavailability. A self-microemulsifying drug delivery system (SMEDDS) was used to enhance the oral bioavailability and lymphatic uptake and transport of Hup-A. A single-pass intestinal perfusion (SPIP) technique and a chylomicron flow-blocking approach were used to study its intestinal absorption, mesenteric lymph node distributi...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica Sinica B
سال: 2017
ISSN: 2211-3835
DOI: 10.1016/j.apsb.2017.02.002